State funding now open to help Ohio innovators commercialize new tech

The Ohio Department of Development has opened a new round of funding to help entrepreneurs and researchers across the state bring cutting-edge technologies to market.

Through its Technology Validation and Start-up Fund (TVSF), the Ohio Third Frontier initiative is now accepting proposals for both Phase 1 and Phase 2 projects. These competitive grants are designed to support commercialization efforts from research labs to startup companies, with a goal of turning promising discoveries into market-ready products.

“By assisting the companies and institutions behind the latest technologies, we’re keeping Ohio at the forefront in the global marketplace and building pathways for the boldest ideas to continue to be created right here in Ohio," said Lydia Mihalik, director of the Department of Development and chair of the Ohio Third Frontier Commission.

How It Works

Phase 1 awards range from $200,000 to $1 million and are aimed at Ohio-based research institutions. The funding supports prototype development, market validation, and proof-of-concept work—with a required 1:1 cost match.

Institutions may also apply for $100,000 grants that waive the cost-share requirement if the project includes hiring an intern.

Phase 2 awards are up to $200,000 and go directly to Ohio startups. These grants help commercialize technologies developed at state universities and research labs by supporting licensing and product validation.

TVSF awards have previously helped launch startups in sectors like advanced manufacturing, biomedical, AI, materials, energy, sensors, and IT, with many recipients later securing follow-on funding from Ohio’s Pre-Seed Fund network.

Key Dates

  • Written questions on the RFP are due by August 1

  • Final proposals are due by 4 p.m. on August 8

  • Awards will be announced in October 2025

Earlier this month, the Department of Development approved $1.1 million in TVSF awards to support six Ohio-based companies working on AI and medical technology commercialization.

Why It Matters

The TVSF program plays a central role in Ohio’s innovation economy—bridging the gap between research breakthroughs and private-sector success. The latest round of funding reaffirms the state’s commitment to growing its tech ecosystem by backing local talent and new ventures.

More information and application details can be found at: Development.Ohio.gov/TVSF

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