Startups + VC
The state’s tech ecosystem is rapidly maturing, driven by massive three-year revenue gains from Keyfactor, CHAMP Titles, and TradingView. These rankings confirm that Ohio software firms have moved well beyond startup mode to successfully compete on the national stage.
Startups + VC
RWX’s new container image builder attacks one of the slowest parts of shipping software: turning code into Docker images. By rethinking builds from first principles inside CI, the team says it can slash wait times and unlock faster, AI-driven development. And it’s being built in Ohio, not SF or NYC.
Workforce + Education
Marietta College has opened the Center for Appalachian Innovation, a state-supported hub focused on research, collaboration, and capacity-building across Appalachian Ohio.
Artificial Intelligence
Ohio has launched “Eva,” a first-of-its-kind AI assistant that gives election officials instant, verified guidance on Ohio’s voting rules. Available to all 88 counties, the tool is designed to speed up routine decisions and strengthen consistency across the state.
Artificial Intelligence
Cleveland-based MorelandConnect has launched FOUNDATION, an AI platform for mid-market companies that unifies business data, delivers instant insights through chat, and enables secure, scalable automation—helping organizations adopt and deploy AI in weeks, not months.
Startups + VC
Columbus-based Healthy Roster has acquired concussion tech leader Sway Medical, uniting two sports medicine innovators into one digital platform for injury documentation and athlete wellness—backed by New York’s Level Equity.
Startups + VC
Cleveland-based Neuronoff raised $4.5M to bring its Injectrode—an injectable, minimally invasive chronic pain treatment—to market by 2026, offering a drug-free, surgery-free alternative to traditional neuromodulation therapies.
Artificial Intelligence
The University of Cincinnati is launching Bearcats AI Ready!, a campus-wide initiative embedding artificial intelligence across teaching, research, and operations to move the university from “AI-fluent” to fully “AI-ready.”
Startups + VC
Cincinnati-based Edge Energy has secured a $3.5 million investment from Germany’s PRETTL Mechatronics & Actuators GmbH to accelerate deployment of its EdgeEV™ Power Source technology, which enables ultra-fast EV charging without costly grid upgrades.
Economic Development
Ohio Governor Mike DeWine announced 12 new business expansion projects expected to create 1,126 jobs and deliver more than $2 billion in total investment statewide.
Artificial Intelligence
Nationwide is making a $1.5 billion investment through 2028 to accelerate technology and AI innovation, including $100 million a year dedicated to artificial intelligence.
Startups + VC
Cleveland Clinic is partnering with DASI Simulations to co-develop an AI “co-pilot” system for heart procedures — using predictive modeling and real-time guidance to enhance safety and precision in TAVR and other structural heart interventions.