Cleveland Clinic, Khosla Ventures join forces to accelerate health tech innovation
Cleveland Clinic is teaming up with Silicon Valley’s Khosla Ventures in a new collaboration designed to fast-track the future of healthcare innovation. The partnership links Ohio’s world-class medical research and clinical expertise with one of the nation’s top venture firms.
Cleveland Clinic and Khosla Ventures announced a strategic collaboration that pairs one of the world’s premier health systems with one of Silicon Valley’s most influential venture firms — aiming to transform how new healthcare technologies move from idea to impact.
The partnership, revealed at the Cleveland Clinic Life Sciences Summit yesterday in London, gives Khosla-backed startups access to Cleveland Clinic’s clinical expertise and real-world testing environments, while providing the Clinic a direct pipeline to emerging innovations in artificial intelligence, digital health, and therapeutics.
Why it matters
The collaboration connects two power centers — Cleveland’s medical excellence and Silicon Valley’s startup ecosystem — at a time when AI and advanced data tools are rapidly reshaping medicine.
It positions Ohio as a key node in the global race to develop, validate, and deploy next-generation healthcare technologies.
The details
Clinical validation and commercialization: Khosla Ventures portfolio companies can work directly with Cleveland Clinic providers to validate and scale new technologies — from early-stage prototypes to commercial adoption.
Access to innovation: Cleveland Clinic gains early insight into emerging solutions across AI, digital health, and precision therapeutics.
Joint incubation: The organizations are exploring the creation of a new co-founded company, with Khosla leading technical development and recruiting, and Cleveland Clinic providing the clinical testbed.
Strategic focus areas:
AI and digital health: automating workflows, improving diagnostics, and personalizing care.
Therapeutics and diagnostics: innovations in cardiology, oncology, neurology, and musculoskeletal care.
Care delivery models: from home-based services to global second-opinion programs.
Value-based care: models tailored for Medicare, Medicaid, and dual-eligible populations.
The big picture
Cleveland Clinic Innovations — which has launched more than 100 spin-off companies and licensed over 900 technologies — will play a central role in guiding projects from lab to market.
For Ohio, the collaboration underscores the state’s growing role as a national leader in health innovation, connecting world-class research with cutting-edge AI and expertise from one of the world’s leading venture investors.
