Spotlights
Haima Therapeutics co-founder Christa Pawlowski is developing SynthoPlate, a synthetic, shelf-stable drug that stops severe bleeding. By transforming Case Western research into lifesaving tech, she is helping establish Ohio as a premier hub for scaling global life science companies.
Healthcare
Amazon One Medical continues its Northeast Ohio expansion with a new tech-enabled office in Shaker Heights. The Van Aken hub integrates 24/7 virtual care with Cleveland Clinic’s specialty network, offering a modern, hybrid approach to relationship-based primary care.
Spotlights
Patricia Colella leads SportsLand™, an initiative positioning Ohio as a national hub for sports tech. Her "moonshot" vision is the Human Performance & Sports Innovation Corridor, a statewide network linking hospitals and startups to accelerate healthcare discovery and economic growth.
Healthcare
Doubling its recent funding, this Cleveland Clinic spinout is scaling a robotic platform to replace animal testing. The technology creates consistent human cells that aim to solve pharma’s reproducibility crisis, cementing Northeast Ohio’s role in the "NAMs" revolution.
Statewide Roundups
Our analytics revealed an undeniable trend: you care about the mega-builds. From defense hubs to crypto banks, the most-viewed stories of 2025 weren't about potential—they were about production. See how the physical and financial backbone of American innovation is being built in Ohio.
Healthcare
Columbus startup DNA Nanobots has secured $3.5 million to revolutionize gene therapy without using viruses. The Ohio State spinout utilizes "DNA origami" to engineer self-assembling vessels that deliver complex payloads. This fresh capital extends their runway to 18 months for future advancements.
Statewide Roundups
From a $1B AI supercluster in Springfield to 15-minute drone deliveries in Dayton, Ohio’s high-tech pivot has moved from potential to proven results. We’re tracking $2B in new expansions and the innovators under 35 who are building the next generation of the Buckeye State.
Healthcare
The expansion adds 400 jobs and a state-of-the-art lab facility to New Albany. Breaking ground in 2026, the move doubles the company's footprint and reinforces Central Ohio's growing reputation as a critical national ecosystem for scaling innovative, tech-enabled patient care.
Startups + VC
By acquiring Flatiron Health's research unit and securing $78M, Paradigm Health creates the largest U.S. oncology research network. The deal embeds clinical trials directly into local exam rooms, aiming to fix the industry's "zip code problem" and democratize access to life-saving therapies.
Startups + VC
Cleveland Clinic is partnering with DASI Simulations to co-develop an AI “co-pilot” system for heart procedures — using predictive modeling and real-time guidance to enhance safety and precision in TAVR and other structural heart interventions.
Workforce + Education
JobsOhio, OLS, and One Columbus launched a multimillion-dollar biomanufacturing workforce initiative. This major bet on biotech aims to train Ohioans for high-demand roles in pharmaceutical production and biotechnology, accelerating the state's growth.
Startups + VC
Avandra Imaging raised $17.75M and relocated to Brecksville to build a federated medical imaging network. Backed by Aegis and SpringRock Ventures, the startup aims to index 1 trillion images, solving critical data silos to accelerate AI and biopharma breakthroughs.