Startups + VC
Spun out of Ohio's veteran venture studio, this new independent, for-profit firm aims to bridge the coastal funding gap by targeting enterprise AI, deep tech, and life sciences. Backed by a strong Central Ohio network, the team delivers critical talent, customers, and execution strategy.
Healthcare
Creative Destruction Lab is partnering with University Hospitals and Case Western to launch CDL-Cleveland. By embedding a global tech accelerator directly into an active health system, local leaders aim to solve the grueling adoption gap and boost Northeast Ohio's startup density.
Healthcare
A mulit-city expansion marks the regional execution of Hikma’s $1B onshore strategy, positioning the Ohio Discovery Corridor as a primary firewall against critical U.S. drug shortages while reinforcing the Midwest's rise in advanced biopharma manufacturing.
Capital + Deals
The major medtech exit highlights a massive win for Northeast Ohio’s biomedical sector. By absorbing the homegrown leader in non-opioid pain therapies, the global healthcare giant secures an FDA-cleared, temporary device that alters how physicians treat chronic pain.
Startups + VC
More than half of Central Ohio’s 55 venture deals in 2025 involved Rev1-backed companies. Led by growth in AI, software, and life sciences, the regional ecosystem continues to secure meaningful exits and concentrate activity around anchor institutions like Rev1.
Capital + Deals
The evergreen platform added 18 new institutional and private investors in Q1, expanding its total backer base to 155 across the state. Total active deployment reached $217M across 33 multi-asset investments, including a $25M manufacturing expansion.
Statewide Roundups
From a 249-person gathering in Cleveland to 827 leaders in Columbus, the milestone data points reveal how the state's flagship tech conference has expanded. The multi-state draw brought together 55 speakers, 30+ sponsors, and a waitlist that grew into triple digits.
Statewide Roundups
The fifth annual Ohio Tech Summit drew 827 founders, operators, investors, and policymakers to Ohio State — sold out, with travelers in from Pittsburgh to Denver. Inside a day on applied AI, re-industrialization, and the Ohio companies turning the state's structural advantages into products.
Partner Content
Columbus-based Aplos Data emerged from stealth as a Platinum Sponsor of the Ohio Tech Summit. Specializing in Palantir Technologies, the firm unifies fragmented tools into a single operational layer, helping organizations "Operate as One" through real-world AI implementation.
Statewide Roundups
The 2026 Ohio Tech Summit brings together Fortune 500 executives, investors, and founders at The Ohio State University on May 14. Featuring leaders from Nationwide, Path Robotics, and a keynote by Ratmir Timashev, the sold-out event explores the future of AI and re-industrialization.
Spotlights
Ohio tech leaders remain invested because the state has moved beyond early-stage hype into a period of execution and scale. By pairing deep industrial expertise with favorable tax policies and a maturing network of research and capital, Ohio offers a durable foundation for global innovation.
Startups + VC
Beam Benefits founder Alex Frommeyer is back with Stack Health, a Columbus-based startup aiming to upend the U.S. insurance market. By shifting coverage from employers to individuals, Stack uses AI to help Ohio workers build personalized, cost-effective health bundles.